MT1 MT2 مسحوق تبييض البشرة mt 1 ببتيدات melanotan i

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٣٠٫٠٠ US$ - ٦٥٫٠٠ US$ / صندوق | 1 صندوق / صناديق (مين. النظام)
الشحن:
الدعم الشحن البحري
Lead Time:
الكمية( صناديق) 1 - 5000 >5000
الوقت المقدر (بالأيام) 3 قابل للتفاوض
تقرير النشاط المشبوه
نظرة عامة
تفاصيل سريعة
CAS No.:
75921-69-6
Other Names:
MT-1
MF:
C78H111N21O19
EINECS No.:
N/M
مكان المنشأ:
Shaanxi, China
نوع:
الفيتامينات والأحماض الأمينية والإنزيمات المساعدة, المواد المساعدة والمواد الكيميائية الطبية الأخرى
الصف القياسي:
درجة مستحضرات التجميل, نوع طبي
استعمال:
الأدوية الحيوانية
اسم العلامة التجارية:
فرصة
رقم الموديل:
فرصة-75921-69-6
نقاء:
99% ٪ دقيقة
اسم المنتج:
Melanotan أنا
المظهر:
مسحوق أبيض
الفحص:
HPLC 99%
التعبئة:
1 صندوق/صناديق
الصف:
الطب الصف
تطبيق:
الخام الدوائية وسيطة
الجرف الحياة:
2 سنوات
شهادة:
ISO
كاس:
75921-69-6
إسم _ أسامي _ أسماء العلامة _ العلامة _ العلامات _ العلامة _ التجارية:
فرصة
قدرة العرض
قدرة العرض:
5000 Box/Boxes per Month We can also produce as you require quality and quantity
التعبئة والتغليف والتوصيل
ميناء
any port in China
مثال للصورة:
package-img
package-img
Lead Time :
الكمية(Boxes) 1 - 5000 >5000
الوقت المقدر (بالأيام) 3 من المقرر التفاوض فيه
Video Description

       Skin Whitening powder mt 1 polypeptides melanotan i

Name: Melanotan-1
Synonyms: Melanotan; Melanotan-1; Melanotan I; CUV1647; EPT1647; NDP-MSH; [Nle4, D-Phe7]α-MSH
CAS No.: 75921-69-6
Molecular Formula: C78H111N21O19
Molecular Mass: 1646.85 Da (g/mol)
Amino Acid Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2

Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide , called alpha-Melanocyte stimulating or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141 have been studied at length as a potential remedies for the treatment of sexual dysfunction, Melanotan-1 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

Both Melanotan-1 and Melanotan-2 are analogs of the peptide alpha-melanocyte stimulating (α-MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan-1 is a non selective agonist of the melanocortin receptors (MC1R,MC3-5R). As an analogue of α-MSH, its mechanism of action is biomimicry of the natural mammalian tanning process.

 The initial creation of the Melanotan 1 peptide tanning analogue can be credited to the University of Arizona. During the course of study aimed at developing a defense against skin cancer, focus was placed on developing a method of stimulating natural melanogenesis, or the natural production of melanin in the skin, without direct exposure to the potentially harmful ultraviolet radiation in sunlight. Initially, University of Arizona researchers attempted to directly administer the naturally occurring alpha-MSH in order to elicit this desired result. Although this strategy exhibited promising results, it was determined that the naturally occurring MSH had a prohibitively short half-life to be of realistic use as a therapeutic remedy. However, the positive results gleaned from MSH administration encouraged further research into the development of Melanotan 1, which exhibits similar effects whilst possessing an extended half-life for functional therapeutic utilization. The researchers, headed by Victor J. Hruby and Mac E. Hadley, found a peptide, [Nle4, D-Phe7]-α-MSH, that was approximately 1,000 times more potent than natural α-MSH. They named this new peptide molecule "Melanotan" (later Melanotan-1).

Melanotan produces its photoprotective effects by triggering a 'signaling cascade' via its activation of the MC1R on melanin-producing cells known as melanocytes. Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin, it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin (photoprotective black/brown pigment). The initial binding activates the MC1R leading to the activation of adenylate cyclase (AC) and stimulation of the production of cyclic adenosine monophosphate (cAMP). cAMP in turn activates protein kinase A (PKA) resulting in the phosphorylation of the cAMP response element-binding (CREB). Phosphorylated CREB will bind to the cAMP response element (CRE) on the microphthalmia-associated transcription factor (MITF) gene leading to the synthesis of the MITF protein. MITF has the ability to activate several genes by binding to them, including the MC1R gene and the genes involved in melanogenesis. This results in increased concentrations of the melanogenic enzymes within the melanocyte.

 

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 Xi’an Chance Bio-Tech Co.,Ltd is located in Chan ba Zone, Xi'an, Shaanxi Province,China. Our company is specialized in producing and selling plant extract and raw material medicine and cosmetic, food additive. We have have done this business for many years. We always believe that trust is the first. We can ensure to offer our clients the best quality of product and service. Sincerely hope to cooperate with you.

We have the most advanced production and test equipments, which can significantly enhance the rationality and accuracy of test. Meanwhile, employees of test department must also abide by the standard operational procedures made for them, thus to examine, monitor and verify the production environment, raw materials and products in different phases, and to conduct data management and analysis for innovation and improvement in the standardized practice.

 

 

 

FAQ

 

Q1: Can i get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

 

Q2: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Paypal or Escrow(Alibaba).

 

Q3: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.

 

Q4:What’s your MOQ?
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

 

Q5: How about delivery leadtime?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

 

Q6:Is there a discount?
A:Different quantity has different discount.

 

Q7: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

 

Q8: How to contact us ?
A:You can chat with us by Trademanager, Whatsapp&Skype Online.
You can choose your interested products and send inquiry to us.
You can dial our telephone directly, you will get our reply.
Send Email to us.

 

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